How can proteolutions help you?

By using a gene sequence optimized by proteolutions, you significantly increase your chances of achieving high-yield, soluble protein expression - across any host system and at any scale. Whether you’re conducting exploratory expression studies in academia or scaling up for industrial protein production, our optimized sequences can be a true game changer, streamlining your workflow and boosting success rates at every step.

Industry

In industrial biotechnology, for medicine or consumer products, soluble and functional proteins at high quantities are required and thus produced in suitable expression hosts. We at proteolutions believe that these processes can be still improved in their efficiency and sustainability. Test proteolutions gene optimization to add value to your protein production process by multiplying your soluble protein yields. Please contact us with your commercial inquiry.

Academia

Soluble target proteins are key to many academic research projects. Here, one difficulty is the explorative character of protein expression. Exotic source organisms, protein fragments, AI-derived and entirely novel protein sequences can result in difficulties with protein production. proteolutions will provide you the best possible optimized gene sequences for your expression needs. Start your optimization here.

Sustainability

Sequences from gene optimization protocols or wild-type genes, both typically like foreign languages to a heterologous expression host, often result in low yields of soluble target protein causing high production costs. This is an ideal scenario for proteolutions gene optimization where we have already observed several-fold higher protein yields and reliable expression for multiple targets. Why not try proteolutions optimized genes to increase sustainability while reducing your energy consumption, raw materials demand and overall protein production costs? Read what our customers say about us.

Failed Expressions Recovery

Despite all efforts, you cannot find a trace of your expressed target protein even on a Western blot? We have compiled several proof-of-principle cases where proteolutions gene optimization has yielded soluble target proteins while other optimization protocols failed entirely, i.e. insolubility of the target protein or no protein observed at all.

AI Designed Proteins

The recently developed AI-based protein design will yield completely artificial protein (and thus nucleotide) sequences unknown in nature. Traditional gene optimization will not be able to cope with this level of sequence complexity. proteolutions optimized genes guarantee a maximum level of adaptation to the production host as already showcased in several instances.

Custom Gene Optimization

Whether you require 44 % AT content or a specific codon bias in your synthetic genes. Inquire at proteolutions for a custom gene optimization at inquiries@proteolutions.com.