Test Your Sequence

The proteolutions score is our measure of DNA sequence quality for soluble heterologous protein expression. It quantifies the extent of favorable triple codon adjacency in your expression host mirroring an ideal and holistic codon network. Based on our expression data ranging from bacterial to mammalian systems, we observe a strong correlation between the proteolutions score and actual soluble protein yields.

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Genetic Code

01 - Standard Code 02 - Vertebrate Mitochondrial Code 03 - Yeast Mitochondrial Code 04 - Mold, Protozoan, and Coelenterate Mitochondrial Code and the Mycoplasma/Spiroplasma Code 05 - Invertebrate Mitochondrial Code 06 - Ciliate, Dasycladacean and Hexamita Nuclear Code 09 - Echinoderm and Flatworm Mitochondrial Code 10 - Euplotid Nuclear Code 11 - Bacterial, Archaeal and Plant Plastid Code 12 - Alternative Yeast Nuclear Code 13 - Ascidian Mitochondrial Code 14 - Alternative Flatworm Mitochondrial Code 16 - Chlorophycean Mitochondrial Code 21 - Trematode Mitochondrial Code 22 - Scenedesmus obliquus Mitochondrial Code 23 - Thraustochytrium Mitochondrial Code 24 - Rhabdopleuridae Mitochondrial Code 25 - Candidate Division SR1 and Gracilibacteria Code 26 - Pachysolen tannophilus Nuclear Code 27 - Karyorelict Nuclear Code 28 - Condylostoma Nuclear Code 29 - Mesodinium Nuclear Code 30 - Peritrich Nuclear Code 31 - Blastocrithidia Nuclear Code 33 - Cephalodiscidae Mitochondrial UAA-Tyr Code

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Sequence Parameters

Type

Nucleotide Amino acid

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Stop

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Select Expression Host

Expression Host

Arabidopsis thaliana Aspergillus niger Aspergillus oryzae Bacillus amyloliquefaciens Bacillus licheniformis Bacillus subtilis Bacillus thermotolerans Bacillus thuringiensis Bombyx mori Chlamydomonas reinhardtii Chlorella variabilis Corynebacterium glutamicum Cricetulus griseus Cyanidioschyzon merolae Drosophila melanogaster Escherichia coli Haloferax volcanii Homo sapiens Kluyveromyces lactis Komagataella phaffii Lactococcus lactis Methanococcus maripaludis Mus musculus Neurospora crassa Phaeodactylum tricornutum Pichia pastoris (Komagataella phaffii) Pseudomonas aeruginosa Pseudomonas fluorescens Pseudomonas putida Pseudomonas syringae Rattus norvegicus Rhodococcus erythropolis Saccharomyces cerevisiae Schizosaccharomyces pombe Spodoptera frugiperda Streptomyces coelicolor Streptomyces griseus Streptomyces lividans Thermosynechococcus elongatus (Thermosynechococcus vestitus) Thermosynechococcus vestitus Thermus thermophilus Trichoderma atroviride Trichoderma harzianum Trichoderma reesei Trichoplusia ni Yarrowia lipolytica

or select one commonly used target species

Escherichia coli Homo sapiens Mus musculus Spodoptera frugiperda Trichoplusia ni